Reflections on chronic hand eczema – Authors’ reply.
Authors: Bissonnette R, Warren RB, Pinter A, Agner T, Gooderham M, Schuttelaar MLA, Crépy MN, Stingeni L, Serra-Baldrich E, Baranowski K, Korn S, Kurvits M, Plohberger U, Strange Vest N, Schliemann S. Read more on pubmed
Guselkumab binding to CD64+ IL-23-producing myeloid cells enhances potency for neutralizing IL-23 signaling.
Authors: Sachen KL, Hammaker D, Sarabia I, Stoveken B, Hartman J, Leppard KL, Manieri NA, Bao P, Greving C, Lacy ER, DuPrie M, Wertheimer J, Deming JD, Brown J, Hart A, Li HH, Freeman TC, Keyes B, Kohler K, White I, Karpowich N, Steele R, Elloso MM, Fakharzadeh S, Goyal K, Lavie F, Abreu MT, Allez […]
Long-term safety and efficacy of delgocitinib cream for up to 52 weeks in adults with Chronic Hand Eczema: results of the phase 3 open-label extension DELTA 3 trial following the DELTA 1 and 2 trials
Authors: Gooderham M, Molin S, Bissonnette R, Worm M, Crépy MN, Stingeni L, Warren RB, Schliemann S, Schuttelaar ML, Ferrucci S, Serra-Baldrich E, Silverberg JI, Balita-Crisostomo CL, Oesterdal ML, Plohberger U, Agner T. Read more on pubmed
Mission impossible? Caveats in interpreting and comparing long-term efficacy in biologic studies for moderate-to-severe plaque psoriasis
Authors: Langley RG, Egeberg A, Gooderham M, Bissonnette R, Ringuet J, Kalia S, Park-Wyllie L, Abbarin N, Tran D, Zara A, Yang YW, Strober B. Read more on pubmed
ROCKET: a phase 3 program evaluating the efficacy and safety of rocatinlimab in moderate-to-severe atopic dermatitis
Authors: Guttman-Yassky E, Simpson E, Bissonnette R, Eichenfield LF, Kabashima K, Luna PC, Hercogová JT, Spelman L, Worm M, Esfandiari E, Arai T, Mano H, Charuworn P, Wang A, Kricorian G. Read more on pubmed
Longitudinal integrated proteomic and metabolomic skin changes in patients with atopic dermatitis treated with dupilumab.
Authors: Goleva E, Berdyshev E, Kreimer S, Reisz JA, D’Alessandro A, Bronova I, Lyubchenko T, Richers BN, Hall CF, Xiao O, Bronoff AS, Bafna S, Agueusop I, Gloaguen E, Zahn J, Bissonnette R, Zhang A, Leung DYM. Read more on pubmed
Skin Tape Stripping Reveals Distinct Biomarker Profiles in Chronic Hand Eczema of Patients With and Without Comorbid Atopic Dermatitis
Authors: Bar J, Del Duca E, David E, Bose S, Chefitz G, Brunner PM, Bissonnette R, Guttman-Yassky E. Read more on pubmed
A Maximum-Use Trial of Ruxolitinib Cream in Children Aged 2-11 Years with Moderate to Severe Atopic Dermatitis
Date: 2024-11-17 Authors: Linda Stein Gold, Robert Bissonnette, Seth Forman, Andrea Zaenglein, YuTzu Kuo, Brett Angel, Xuejun Chen, Howard Kallender, Amy S Paller Category: Dermatitis (all types), Eczema Background: Ruxolitinib cream has demonstrated anti-inflammatory and antipruritic activity and was well tolerated in a phase 3 study in patients aged 2-11 years with mild to moderate atopic dermatitis (AD). Objective: This […]
FRONTIER-2: A phase 2b, long-term extension, dose-ranging study of oral JNJ-77242113 for the treatment of moderate-to-severe plaque psoriasis
Date: 2024-11-14 Authors: Laura K Ferris 1, Jerry Bagel2, Yu-Huei Huang3, Andrew E Pink4, Stephen K Tyring5, Georgios Kokolakis6, Amy M DeLozier7, Shu Li8, Yaung-Kaung Shen8, Charles Iaconangelo8, Takayuki Ota7, Robert Bissonnette9 Category: Psoriasis Background: More patients with moderate-to-severe plaque psoriasis achieved responses with JNJ-77242113, a targeted oral peptide inhibiting interleukin-23 receptor signaling, versus placebo (PBO) at week (W)16 of the phase 2 FRONTIER-1 study. Objective: FRONTIER-2, a long-term extension of […]
Hand Eczema. Part 1: epidemiology, pathogenesis, diagnosis and work-up
Date: 2024-10-05 Authors:Robert Bissonnette 1, Tove Agner2, Sonja Molin3, Emma Guttman-Yassky4 Category: Eczema Read more on pubmed
