Topic: Dermatology

Icotrokinra induces early and sustained pharmacodynamic responses in phase IIb study of patients with moderate-to-severe psoriasis

Authors: David Strawn, James G Krueger, Robert Bissonnette, Kilian Eyerich, Laura K Ferris, Amy S Paller, Andreas Pinter, Dylan Richards, Elizabeth Y Chen, Kate Paget, Daniel Horowitz, Roohid Parast, Joshua J Rusbuldt, Jocelyn Sendecki, Sunita Bhagat, Lynn P Tomsho, Ching-Heng Chou, Marta E Polak, Brice E Keyes, Emily Bozenhardt, Yuan Xiong, Wangda Zhou, Cynthia DeKlotz, […]

Rapid Transcriptomics Brings Actionable Data to Early-Phase Topical Trials

In this article published by Today’s Clinical Lab, Stéphanie Légaré, Scientific Advisor at Indero, shares about early transcriptomic readouts reveal pharmacodynamic activity in skin within days—a shift toward earlier molecular decision-making. Read More

Episode 37: Simon Grant (Ascilion) & Théo Boyer – ISF: A New Dimension in Skin Biomarkers

Resources:  [email protected]: Use this email to let us know what you want to hear about.  https://www.ascilion.com/    This episode explores the future of skin biomarkers. Featuring insights from Simon Grant, CEO of Ascilion, and Théo Boyer, Senior Project Coordinator at Indero, the episode examines how dermal interstitial fluid (d-ISF) could revolutionize dermatology. Our guests illuminate […]

Top Dermatology Conferences to Attend

The dermatology clinical research industry thrives on innovation, collaboration, and scientific advancements. Conferences are essential in nurturing these aspects, offering platforms for experts to exchange knowledge, discuss breakthroughs, and join forces to achieve the ultimate common goal: discovering new therapies and improving patients’ lives. Here, we highlight the top dermatology conferences that make significant contributions […]

Targeted Oral Peptide Icotrokinra for Psoriasis Involving High-Impact Sites

Authors: Gooderham M, Lain E, Bissonnette R, Huang YH, Lynde CW, Hoffmann M, Song EJ, Weirich O, Ceitlin RHG, Rubens JH, Delozier AM, Ota T, Hsu M-C, Li S, DeKlotz CMC, Nunes F, Warren RB Read more on pubmed

Efficacy and safety of rocatinlimab for the treatment of moderate-to-severe atopic dermatitis in ROCKET-IGNITE and ROCKET-HORIZON: two global, double-blind, placebo-controlled, randomised phase 3 clinical trials

Authors: Guttman-Yassky E, Kabashima K, Worm M, Luna PC, Hong CHH, Chovatiya R, Berstein JA, Kern JS, Ehst BD, Magnolo N, Herranz-Pinto P, Stein Gold L, Sofen H, Pink AE, Esfandiari E, Arai T, Shi R, Barragan C, Kricorian G, Schwartz-Sagi L, Bissonnette R Read more on pubmed

Interview with Dr. Robert Bissonnette: Indero Introduces New Early Phase 1 Model for Topical NCEs, Shortening Study Duration from 8-12 Weeks to ≤3 Days

  In this exclusive interview, Dr. Robert Bissonnette shares insights from Indero’s internally-led study, which introduces a novel approach to early phase topical drug evaluation. By leveraging quantitative gene expression analysis and non-invasive tape strip sampling, this method promises to transform the assessment of new chemical entities (NCEs), offering rapid, cost-effective, and patient-friendly solutions for […]

Ruxolitinib Cream Demonstrated Rapid Reductions in Itch and Atopic Dermatitis Signs That Correlated With Biomarkers

Authors: Bissonnette R, Saint-Cyr Proulx, E, Correa da Rosa J, Estrada Y, Ren H, Nawaz H, Halden P, Stefani-Hunyady D, Popovic K, Volkova A, Smith SH, Guttman-Yassky E Read more on pubmed

The SWITCH algorithm: An expert consensus on treat-to-target criteria for chronic prurigo

Authors: Stahl LS, Zeidler C, Loewenthal J, Royeck S, Augustin M, Bissonnette R, Elmariah S, Kim BS, Misery L, Murota H, Liang Tey H, Weisshaar E, Yosipovitch G, Legat FJ, Reich A, Metz M, Stander S Read more on pubmed

Oral Icotrokinra for Plaque Psoriasis in Adults and Adolescents

Authors: Bissonnette R, Soung J, Hebert AA, Pink AE, Pinter A, Moor AY, Shi Y, Wang W-H, Toth DP, Miller-Kassamali M, Cafone J, Jiang J, Li S, DeKlotz CMC, Nunes F, Lebwohl MG Read more on pubmed