Dr.âŻRobert Bissonnette and Dr.âŻKim Papp on the Intricacies of Dermatology Early Phase Clinical Research
In collaboration with Probity Medical Research (PMR) Amidst the bustling 2023 EADV in Berlin, Dr. Bissonnette from Innovaderm Research and Dr. Papp from Probity Medical Research (PMR) found a unique opportunity for an engaging conversation. The pair covered some of the main challenges encountered with conducting vitiligo studies and insights on alopecia areata (AA) studies. This article will focus on […]
3 Tips for Collecting Samples with Tape Stripping
Tape Stripping is a non-invasive option for the study of biomarkers in dermatology studies. Innovaderm is sharing its 3 best tips when performing tape strip collections. Letâs cover our bases, what is tape stripping? Tape stripping is used in dermatology studies to sample skin surface material by collecting a thin layer of cells from the […]
Next-Gen Drug Development: The AI Advantage
In this article, we explore the transformative impact of Artificial Intelligence (AI) on drug development and clinical trials. We had the opportunity to speak with three distinguished experts in the field: Guillaume Gigon, Vice President of Technology and AI at Indero; Nardin Nakhla, Co-Founder and CTO of Simmunome; and Christian Dansereau, Founder and CEO of […]
Investigating Transdermal Analysis Patch (TAP) as a Non-Invasive Option for Biomarkers Studies
Conventional avenues to collect samples for the analysis of biomarkers have proven to necessitate intrusive procedures, engendering patient aversion and potential procedural hazards. Several recent non-invasive sampling approaches such as tape stripping and transdermal analysis patch (TAP) are making their way in dermatology clinical trials. This article will focus on TAP in an attempt to bring emphasis on the […]
The Intricacies of Multicenter Studies in Alopecia Areata
Alopecia Areata: The Condition Alopecia Areata (AA)Â is a medical condition characterized by hair loss that occurs in patches on the scalp or other parts of the body. The hair loss is not uniform and can vary greatly from patient to patient, with some experiencing minimal hair loss and others losing hair across their entire scalp […]
The Role of Skin barrier Dysfunction in Atopic DermatitisâThe Microbiome
Focusing on the microbiome, Staphylococcus aureus (S. aureus) is a widespread bacterium that produces a multilayer biofilm, was shown to colonize the skin and play a critical role in Atopic Dermatitis (AD). Over 70% of people are colonized, and heavy colonization is associated with skin barrier dysfunction, food allergies and unresponsiveness to cyclosporine. A paper published by Heidi Kong et al. shows that before an AD […]
Atopy and Alopecia Areata: A Leading Pair
Alopecia areata (AA) and atopy, which is a predisposition to develop allergic reactions, share a significant connection. While thyroid complications are often the primary concern in autoimmune diseases, a substantial number of these patients also suffer from allergies and hypersensitivities. In fact, atopic conditions are found in 30% to 50% of AA patients. Importance of Understanding Atopy […]
Exploring the Benefits of Tape Stripping in Dermatology Clinical Research
There are several approaches to study biomarkers using non-invasive techniques such as tape stripping and transdermal analysis patch. This article will focus on the tape stripping method. The popularity of tape stripping in clinical trials has been steadily increasing for the last 19 years. This growing interest can be observed in the number of publications showcasing this non-invasive technique as well […]
How to Write First-Rate Protocols for an Atopic Dermatitis Study – Focus: TREATMENT DURATION AND KEY ELIGIBILITY CRITERIA
In recent years, therapeutics for dermatologic conditions have become a subspecialty of growing interest in the Clinical Research Organisation (CRO) industry, with clinical research in the area focused on a wide range of skin indications, such as acne vulgaris, psoriasis, and atopic dermatitis. What is atopic dermatitis? Atopic dermatitis (AD), also known as atopic eczema, is […]
Using Biomarkers in Clinical Research
Clinical biomarkers ushered in a new era of possibilities in medicine by profoundly impacting the way we investigate and develop new treatment options. Non-invasive techniques such as tape stripping and transdermal analysis patch (TAP) are transforming the dermatology clinical landscape. Biomarkers in clinical trials measure changes in protein, gene expression, or other biochemical pathways associated […]
